Disruption of membrane integrity by the bacteria-derived antifungal jagaricin.

Fischer D, Gessner G, Fill TP, Barnett R, Tron K, Dornblut K, Kloss F, Stallforth P, Hube B, Heinemann SH, Hertweck C, Scherlach K, Brunke S

Antimicrob. Agents Chemother. In press. doi: 10.1128/AAC.00707-19

Bioactivity and Mode of Action of Bacterial Tetramic Acids

Klapper M, Paschold A, Zhang S, Weigel C, Dahse H-M, Götze S, Pace S, König S, Rao Z, Reimer L, Werz O, Stallforth P

ACS Chem. Biol. In press. doi: 10.1021/acschembio.9b00388


The chemoattractant glorin is inactivated by ester cleavage during early multicellular development of Polysphondylium pallidum

Heinrich D, Barnett R, Tweedy L, Insall R, Stallforth P, Winckler T

ACS Chem. Biol. 13, 1506.

Synthesis, Liposomal Formulation, and Immunological Evaluation of a Minimalistic Carbohydrate-α-GalCer Vaccine Candidate

Broecker F, Götze S, Hudon J, Rathwell DCK, Pereira CL, Stallforth P, Chakkumkalag A, Seeberger PH

J. Med. Chem. 61, 4918.

Synergistic activity of co-secreted natural products from amoebae-associated bacteria

Arp J, Götze S, Mukherji R, Mattern D, Garcia-Altares M, Klapper M, Brock D, Brakhage AA, Strassmann J, Queller D, Bardl B, Willing K, Peschel G, Stallforth P

Proc. Natl. Acad. Sci. USA 115, 3758.


Bacterial Alkaloid Biosynthesis: Structural Diversity via a Minimalistic Nonribosomal Peptide Synthetase

Klapper M, Braga D, Lackner G, Herbst R, Stallforth P

Cell Chem. Biol. 25, 659.


The Role of Bacterial Natural Products in Predator Defense

Klapper M, Arp J, Günther M, Stallforth P

Synlett, 29, 537.

Natural Products from Social Amoebae

Barnett R, Stallforth P

Chem. Eur. J, 24, 4202.


Structure, Biosynthesis, and Biological Activity of the Cyclic Lipopeptide Anikasin

Götze S, Herbst-Irmer R, Klapper M, Görls H, Schneider KRA, Barnett R, Burks T, Neu U, Stallforth P

ACS Chem. Biol. 12, 2498.


Lysinibacillus fusiformis M5 induces increased complexity in Bacillus subtilis 168 colony biofilms via hypoxanthine

Gallegos-Monterrosa R, Kankel S, Götze S, Barnett R, Stallforth P, Kovács AT

J. Bacteriol. 199:e00204-17.

Rationalizing the Right Ratios

Arp J, Stallforth P

Cell Chem. Biol. 24, 539.

A Versatile Synthesis of the Signaling Peptide Glorin

Barnett R, Raszkowski D, Winckler T, Stallforth P

Beilstein J. Org. Chem. 13, 247.

Bacterial alkaloids prevent amoebal predation

Klapper M, Götze S, Barnett R, Willing K, Stallforth P

Angew. Chem. Int. Ed. 55, 8944


Three Redundant Synthetases Secure Redox-Active Pigment Production in the Basidiomycete Paxillus involutus

Braesel J, Götze S, Shah F, Heine D, Tauber J, Hertweck C, Tunlid A, Stallforth P, Hoffmeister D

Chem. Biol. 22, 1325.

Total Synthesis of Legionaminic Acid as Basis for Serological Studies

Matthies S, Stallforth P, Seeberger PH

J. Am. Chem. Soc. 137, 2848.


A semi-synthetic carbohydrate-lipid vaccine that protects against S. pneumoniae in mice

Cavallari M, Stallforth P, Kalinichenko A, Rathwell DCK, Gronewold TMA, Adibekian A, Mori L, Landmann R, Seeberger PH, DeLibero G

Nat. Chem. Biol. 10, 950.

Atlas for drug discovery

Stallforth P, Clardy J

Proc. Natl. Acad. Sci. USA 111, 3655.

A bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene

Stallforth P, Brock DA, Cantley AM, Tian X, Queller DC, Strassmann JE, Clardy J

Proc. Natl. Acad. Sci. USA 110, 14528.

X-ray crystallography: One size fits most

Stallforth P, Clardy J

Nature 495, 456.


Protein evolution: when two become three

Stallforth P, Clardy J

Curr. Biol. 22, R685.

De novo chemoenzymatic synthesis of sialic acid

Stallforth P, Matthies S, Adibekian A, Gillingham DG, Hilvert D, Seeberger PH

Chem. Commun. 48, 11987.


Chemoenzymatic synthesis of differentially protected 3-deoxysugars

Gillingham DG, Stallforth P, Adibekian A, Seeberger PH, Hilvert D

Nat. Chem. 2, 102.


Recent advances in carbohydrate-based vaccines

Hecht ML, Stallforth P, Silva DV, Adibekian A, Seeberger PH

Curr. Opin. Chem. Biol. 13, 354.

2009 Claude S. Hudson Award in Carbohydrate Chemistry. Carbohydrates: a frontier in medicinal chemistry

Stallforth P, Lepenies B, Adibekian A, Seeberger PH

J. Med. Chem. 52, 5561.